Конференція: Basic medical science for endocrinology 2021
Напрямок: Біохімічні, метаболічні особливості розвитку ендокринних змін
Prevention of metabolic syndrome in pregnant women based on study of body composition
- Dovgan N.A. Communal non-profit enterprise , Odessa, Ukraine
- Plakida A.L. Odessa National Medical University, Odessa, Ukraine
Metabolic syndrome (MS) is a higly significant public health problem. Its prevalence throughout the world is growing steadily every year, and in some countries, it reaches a third of the adult population. Obesity is a major component of MS and a significant independent risk factor for developing many gestational complications. The study included 46 women aged 22 to 41 years. Studies began at 2-4 weeks of gestation and continued until delivery. The bioimpedance method using a body composition monitor “Omron BF-512”, Japan, was used to study the body\'s composition to determine of muscle and fat components, and the level of visceral fat. Biochemical studies included the determination of blood glucose, glucose tolerance, insulin, triglycerides, high and low-density lipoproteins by standard methods. A close relationship was found between the initial value of the fat component and the amount of weight gain during pregnancy. Of prime importance is the amount of weight gain during pregnancy.
- Cornier M-A, Dabelea D, Hernandez TL, Lindstrom RC, Steig AJ, Stob NR, et al. The Metabolic Syndrome. Endocrine Reviews [Internet]. 2008 Dec 1;29(7):777–822. Available from: https://doi.org/10.1210/er.2008-0024
- Franchini M, Targher G, Montagnana M, Lippi G. The metabolic syndrome and the risk of arterial and venous thrombosis. Thrombosis Research [Internet]. 2008 Jan;122(6):727–735. Available from: https://doi.org/10.1016/j.thromres.2007.09.010
- Gluckman PD, Hanson MA, Cooper C, Thornburg KL. Effect of In Utero and Early-Life Conditions on Adult Health and Disease. New England Journal of Medicine [Internet]. 2008 Jul 3;359(1):61–73. Available from: https://doi.org/10.1056/NEJMra0708473
- Kristensen J, Vestergaard M, Wisborg K, Kesmodel U, Secher NJ. Pre-pregnancy weight and the risk of stillbirth and neonatal death. BJOG: An International Journal of Obstetrics and Gynaecology [Internet]. 2005 Apr;112(4):403–408. Available from: https://doi.org/10.1111/j.1471-0528.2005.00437.x
- Lakshmy R. Metabolic syndrome: Role of maternal undernutrition and fetal programming. Reviews in Endocrine and Metabolic Disorders [Internet]. 2013 Sep;14(3):229–240. Available from: https://doi.org/10.1007/s11154-013-9266-4
- Niu JM, Lei Q, Lu LJ, Wen JY, Lin XH, Duan DM et al. Evaluation of the diagnostic criteria of gestational metabolic syndrome and analysis of the risk factors. Zhonghua Fu Chan Ke Za Zhi. 2013 Feb;48(2):92-97.
- Nohr EA, Vaeth M, Bech BH, Henriksen TB, Cnattingius S, Olsen J. Maternal Obesity and Neonatal Mortality According to Subtypes of Preterm Birth. Obstetrics & Gynecology [Internet]. 2007 Nov;110(5):1083–1090. Available from: https://doi.org/10.1097/01.AOG.0000286760.46679.f8
- Yu C, Teoh T, Robinson S. Review article: Obesity in pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology [Internet]. 2006 Aug 10;113(10):1117–1125. Available from: https://doi.org/10.1111/j.1471-0528.2006.00991.x