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Конференція: Фундаментальні науки – практичній медицині: морфо-функціональні методи дослідження онтогенетичних перетворень, фізіологічних та метаболічних процесів, змодельованих патологічних станів, при захворюваннях внутрішніх органів

Напрямок: Морфологія сьогодення.

Reduction of microvascular length in dentate gyrus of the hippocampus of diseased Alzheimer’s rats

Authors

  • Kolinko Yaroslav Biomedical Center in Pilsen, Faculty of Medicine in Pilsen, Charles University, Czech Republic.; Department of Histology and Embryology, Faculty of Medicine in Pilsen, Charles University, Czech Republic.
  • Ježek Karel Biomedical Center in Pilsen, Faculty of Medicine in Pilsen, Charles University, Czech Republic.
  • Marsalová Lucie Biomedical Center in Pilsen, Faculty of Medicine in Pilsen, Charles University, Czech Republic.; Department of Histology and Embryology, Faculty of Medicine in Pilsen, Charles University, Czech Republic.
  • Mouton Peter R SRC Biosciences & Department of Pathology & Cell Biology, School of Medicine University of South Florida, Tampa.
📧Corresponding author

Abstract

Alzheimer’s disease (AD) is accompanied by changes in vascularization and exhibits many emotional abnormalities. In response to the growing interest in the use of a novel transgenic AD model, we aimed of this study to descript features of microcirculation using modern approaches of unbiased stereology to quantify various microcirculation parameters in the pyramidal cell layers of different hippocampal zones of TgF344-AD rats.

Keywords

Alzheimer disease microvessels rat stereology

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References

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